Use all the tools you need to start and be comfortable.
But I suggest to you to start ASAP to build your own tools for sprite/animation/ui creation/bundling as it is a strong part of the identity of a game.
The relevant doc parts are the following:
https://wiki.neogeodev.org/index.php?title=Sprite_graphics_formathttps://wiki.neogeodev.org/index.php?title=Sprites